Peptide Synthesis: Prof. El-Henawy explores the synthesis of novel dipeptide, tripeptide, tetrapeptide, and pentapeptide derivatives with potential antimicrobial activity. This research area involves designing and synthesizing peptide analogs to investigate their bioactivity against microbial pathogens.
Anticancer Agents: He is interested in the synthesis and evaluation of new analogs, such as 2-amino-1,3,4-thiadiazol derivatives, as potential anticancer agents. This research aims to develop novel compounds with enhanced anticancer activity and reduced toxicity profiles.
Small Molecule Drug Design: Prof. El-Henawy is involved in designing and synthesizing small molecule compounds with therapeutic potential. This includes the development of sulfonamide derivatives and other organic molecules with antimicrobial properties.
Biochemical Mechanisms: He investigates the biochemical mechanisms underlying the activity of synthesized compounds, focusing on their interaction with biological targets and elucidating their mode of action. This research contributes to understanding the molecular basis of drug efficacy and toxicity.
Spectroscopic Analysis: Prof. El-Henawy utilizes various spectroscopic techniques, such as UV spectroscopy, FTIR spectroscopy, and NMR spectroscopy, for structural elucidation and characterization of synthesized compounds. These analytical methods provide insights into the chemical structure and properties of organic molecules.