Ahmed Elhenawy | Drug Design | Best Researcher Award

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Prof. Ahmed Elhenawy, Drug Design, Best Researcher Award

Doctorate at Al-Azhar University, Egypt

Summary:

Prof. Ahmed El-Henawy is a distinguished academic and researcher in the field of Chemistry, specializing in organic chemistry and pharmaceutical sciences. He holds a Ph.D. in Organic Chemistry with a focus on amino acids and proteins from Al-Azhar University in Cairo, Egypt. With over a decade of experience in academia, Prof. El-Henawy has served as a lecturer, assistant lecturer, and demonstrator at Al-Azhar University, where he has taught a wide range of undergraduate and postgraduate courses in organic chemistry.

Throughout his career, Prof. El-Henawy has made significant contributions to the field of peptide synthesis, particularly in the design and synthesis of novel peptide derivatives with antimicrobial and anticancer properties. His research interests also extend to the development of small molecule drugs, biochemical mechanisms of drug action, and spectroscopic analysis techniques.

Professional Profile:

Google Scholar Profile

👩‍🎓Education & Qualification:

Ph.D. in Organic Chemistry:

  • Completed at Al-Azhar University, Cairo, Egypt.
  • Thesis Title: “Synthesis and Study of New Amino Acid Derivatives of Expected Biological Activities”.
  • Specialization: Amino Acids & Proteins.
  • Year of Completion: 2005-2008.

Master of Science (M.Sc.) in Organic Chemistry:

  • Earned at Al-Azhar University, Cairo, Egypt.
  • Thesis Title: “Synthesis and Study of Some Amino Acids Derivatives”.
  • Specialization: Amino Acids & Proteins.
  • Year of Completion: 2002-2005.

One-year Graduate Courses for M.Sc. Degree:

  • Partial fulfillment of the requirements for the M.Sc. degree.
  • Chemistry Department, Faculty of Science, Al-Azhar University, Cairo, Egypt.
  • Year: 2001.

Bachelor of Science (B.Sc.) in Special Chemistry:

  • Obtained from Al-Azhar University, Cairo, Egypt.
  • Year of Completion: 2000.

Professional Experience:  

Prof. Ahmed El-Henawy boasts a rich and extensive professional experience in the field of Chemistry, spanning over several roles and institutions. Since August 2008, he has served as a Lecturer in the Chemistry Department at Al-Azhar University, Cairo, Egypt, where he has been actively involved in teaching undergraduate and postgraduate courses, supervising theses, and contributing to curriculum development. Prior to this, from September 2005 to August 2008, he held the position of Assistant Lecturer at the same institution, where he further honed his teaching and academic skills. Prof. El-Henawy began his academic career as a Demonstrator at Al-Azhar University in September 2002, gaining valuable experience in laboratory instruction and student supervision. In addition to his roles at Al-Azhar University, he has also served as an Assistant Professor at Albaha University, Albaha, KSA, from October 2012 to the present, and as a Professor at Al-Azhar University, Cairo, Egypt, from February 2020 to the present. Throughout his career, Prof. El-Henawy has demonstrated a commitment to excellence in education, research, and academic leadership.

Research Interest:

Peptide Synthesis: Prof. El-Henawy explores the synthesis of novel dipeptide, tripeptide, tetrapeptide, and pentapeptide derivatives with potential antimicrobial activity. This research area involves designing and synthesizing peptide analogs to investigate their bioactivity against microbial pathogens.

Anticancer Agents: He is interested in the synthesis and evaluation of new analogs, such as 2-amino-1,3,4-thiadiazol derivatives, as potential anticancer agents. This research aims to develop novel compounds with enhanced anticancer activity and reduced toxicity profiles.

Small Molecule Drug Design: Prof. El-Henawy is involved in designing and synthesizing small molecule compounds with therapeutic potential. This includes the development of sulfonamide derivatives and other organic molecules with antimicrobial properties.

Biochemical Mechanisms: He investigates the biochemical mechanisms underlying the activity of synthesized compounds, focusing on their interaction with biological targets and elucidating their mode of action. This research contributes to understanding the molecular basis of drug efficacy and toxicity.

Spectroscopic Analysis: Prof. El-Henawy utilizes various spectroscopic techniques, such as UV spectroscopy, FTIR spectroscopy, and NMR spectroscopy, for structural elucidation and characterization of synthesized compounds. These analytical methods provide insights into the chemical structure and properties of organic molecules.

Publication Top Noted:

Title: Synthesis and characterization of some arylhydrazone ligand and its metal complexes and their potential application as flame retardant and antimicrobial additives

  • Authors: H Abd El-Wahab, M Abd El-Fattah, AH Ahmed, AA Elhenawy, NA Alian
  • Journal: Journal of Organometallic Chemistry
  • Volume: 791
  • Pages: 99-106
  • Year: 2015
  • Citations: 46

Title: Nano-amino acid cellulose derivatives: Eco-synthesis, characterization, and antimicrobial properties

  • Authors: M Hasanin, A El-Henawy, WH Eisa, H El-Saied, M Sameeh
  • Journal: International Journal of Biological Macromolecules
  • Volume: 132
  • Pages: 963-969
  • Year: 2019
  • Citations: 45

Title: Naproxen based 1, 3, 4-oxadiazole derivatives as EGFR inhibitors: Design, synthesis, anticancer, and computational studies

  • Authors: MM Alam, S Nazreen, ASA Almalki, AA Elhenawy, NI Alsenani, …
  • Journal: Pharmaceuticals
  • Volume: 14
  • Issue: 9
  • Pages: 870
  • Year: 2021
  • Citations: 41

Title: Experimental and theoretical investigation for 6-Morpholinosulfonylquinoxalin-2 (1H)-one and its haydrazone derivate: Synthesis, characterization, tautomerization and …

  • Authors: DM Elsisi, A Ragab, AA Elhenawy, AA Farag, AM Ali, YA Ammar
  • Journal: Journal of Molecular Structure
  • Volume: 1247
  • Pages: 131314
  • Year: 2022
  • Citations: 36

Title: Design, synthesis and molecular docking studies of thymol based 1, 2, 3-triazole hybrids as thymidylate synthase inhibitors and apoptosis inducers against breast cancer cells

  • Authors: MM Alam, AM Malebari, N Syed, T Neamatallah, ASA Almalki, …
  • Journal: Bioorganic & Medicinal Chemistry
  • Volume: 38
  • Pages: 116136
  • Year: 2021
  • Citations: 35

Marwan Kobeissi | Medicinal Chemistry | Best Researcher Award

Posted on by Best Paper Award

Prof. Marwan Kobeissi, Medicinal Chemistry, Best Researcher Award

Professor at Lebanese University, Lebanon

Summary:

Prof. Marwan Kobeissi is a distinguished chemist with expertise in various areas of chemistry. He holds a Ph.D. from a prestigious university in the USA, awarded in 2013. Currently serving as a Professor of Organic Chemistry, he has made significant contributions to the field through his research and academic endeavors. Prof. Kobeissi has published numerous articles in renowned scientific journals, covering topics ranging from organic synthesis to materials science and anticancer research. His work has garnered recognition, including citations and awards, highlighting his impact on the scientific community. With a commitment to excellence in education and research, Prof. Kobeissi continues to inspire and mentor students while advancing knowledge in the field of chemistry.

Professional Profile:

Scopus Profile

👩‍🎓Education & Qualification:

Prof. Marwan Kobeissi’s educational background is as follows:

PhD in Chemistry (1998-2001)

DEA in Molecular Chemistry (1997-1998)

Master’s Degree in General Chemistry (1996-1997)

Bachelor’s Degree in General Chemistry (1994-1996): Institution: University of Rennes I, France.

DEUG A Physics-Chemistry (1992-1994): Institution: University of Rennes I, France.

Professional Experience:         

Prof. Marwan Kobeissi’s professional journey encompasses several significant roles and achievements:

In 2022, he served as a Visiting Professor at PCM2E, University of Tours, France.

Since 2017, Prof. Kobeissi has been the recipient of the “high level scientific stay” grant (SAFAR) from the French Ministry for Europe and Foreign Affairs.

Since 2014, he has been actively involved as the Coordinator of the research Master2 program in Synthesis, Catalysis, and Sustainable Chemistry (SCSCULFS5.2). Additionally, he is the Co-Founder of Rammal Laboratory and serves as the coordinator of the Applied Organic Chemistry research group (SOA)-ULFS5. Furthermore, he holds the position of Professor of Organic Chemistry at ULFS5.

In 2018, Prof. Kobeissi returned to PCM2E, University of Tours, France, as a Visiting Professor.

From 2015 to 2019, he assumed the role of Head of the Chemistry and Biochemistry department at the Lebanese University-ULFS5.

This diverse array of experiences highlights Prof. Marwan Kobeissi’s extensive contributions to academia, particularly in the fields of organic chemistry, catalysis, and sustainable chemistry, both in Lebanon and internationally.

Visiting Professor at PCM2E, University of Tours, France (December 2015). Associate Professor of Organic Chemistry at ULFS5 (2007-2014). Assistant Professor of Chemistry at ULFS5 (2004-2007). Part-time Instructor at Lebanese American University (LAU) and Lebanese International University (LIU). Postdoctoral researcher at the Selective Reactions and Applications Laboratory, UMR 6519, University of Reims, France (2004-2007). His research focused on the use of the Petasis reagent in Organic Synthesis, preparation of functionalized enamines, and their application in the total synthesis of alkaloids under the supervision of Prof. A. Haudrechy. Postdoctoral researcher at the Natural Products Chemistry Institute, CNRS, Gif-sur-Yvette, France (2003-2004). Here, he worked on the total synthesis of non-conventional amino acids for the preparation of marine peptides, along with structural studies and characterizations under the guidance of Drs. C. Poupat and A. Ahond. This comprehensive timeline illustrates Prof. Marwan Kobeissi’s academic and research journey, showcasing his significant contributions and expertise in organic chemistry and synthesis.

Research Interest:

Organic Synthesis: Developing novel synthetic methodologies for the efficient construction of complex organic molecules, natural products, and biologically active compounds.

Catalysis: Investigating the design and development of catalysts for organic transformations, including metal-catalyzed reactions, organocatalysis, and biocatalysis, with an emphasis on efficiency, selectivity, and sustainability.

Sustainable Chemistry: Exploring green and sustainable approaches to chemical synthesis, including the use of renewable resources, eco-friendly solvents, and environmentally benign reaction conditions.

Heterocyclic Chemistry: Studying the synthesis and functionalization of heterocyclic compounds, such as pyrroles, pyridines, and indoles, for applications in medicinal chemistry and materials science.

Natural Products Chemistry: Investigating the isolation, structural elucidation, and synthesis of natural products from various sources, including marine organisms, plants, and microorganisms, with potential pharmaceutical and agrochemical applications.

Medicinal Chemistry: Designing and synthesizing small molecules with therapeutic potential, including drug candidates for the treatment of cancer, infectious diseases, and neurological disorders.

Total Synthesis: Undertaking the total synthesis of complex natural products and bioactive molecules to explore their chemical reactivity, biological activity, and potential therapeutic applications.

Publication Top Noted:

Cyclopentadithiophene and Fluorene Spiro-Core-Based Hole-Transporting Materials for Perovskite Solar Cells

  • Authors: R. Nakar, F.J. Ramos, C. Dalinot, J. Rousset, B. Schmaltz
  • Journal: Journal of Physical Chemistry C
  • Year: 2019
  • Volume: 123
  • Citation count: 17

Synthesis and Anticancer Activity of Gold Porphyrin Linked to Malonate Diamine Platinum Complexes

  • Authors: I. Toubia, C. Nguyen, S. Diring, M. Kobeissi, F. Odobel
  • Journal: Inorganic Chemistry
  • Year: 2019
  • Volume: 58
  • Citation count: 28

A convenient one-pot synthesis of polysubstituted pyrroles from N-protected succinimides

  • Authors: M. Kobeissi, O. Yazbeck, Y. Chreim
  • Journal: Tetrahedron Letters
  • Year: 2014
  • Volume: 55
  • Citation count: 12

Bromination of enamines from tertiary amides using the Petasis reagent: A convenient one-pot regioselective route to bromomethyl ketones

  • Authors: M. Kobeissi, K. Cherry, W. Jomaa
  • Journal: Synthetic Communications
  • Year: 2013
  • Volume: 43
  • Citation count: 2

Synergetic anticancer activity of gold porphyrin appended to phenyl tin malonate organometallic complexes

  • Authors: C. Nguyen, I. Toubia, S. Diring, M. Kobeissi, F. Odobel
  • Journal: Dalton Transactions
  • Year: 2021
  • Volume: 50
  • Citation count: 12