Ahmed Elhenawy | Drug Design | Best Researcher Award

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Prof. Ahmed Elhenawy, Drug Design, Best Researcher Award

Doctorate at Al-Azhar University, Egypt

Summary:

Prof. Ahmed El-Henawy is a distinguished academic and researcher in the field of Chemistry, specializing in organic chemistry and pharmaceutical sciences. He holds a Ph.D. in Organic Chemistry with a focus on amino acids and proteins from Al-Azhar University in Cairo, Egypt. With over a decade of experience in academia, Prof. El-Henawy has served as a lecturer, assistant lecturer, and demonstrator at Al-Azhar University, where he has taught a wide range of undergraduate and postgraduate courses in organic chemistry.

Throughout his career, Prof. El-Henawy has made significant contributions to the field of peptide synthesis, particularly in the design and synthesis of novel peptide derivatives with antimicrobial and anticancer properties. His research interests also extend to the development of small molecule drugs, biochemical mechanisms of drug action, and spectroscopic analysis techniques.

Professional Profile:

Google Scholar Profile

👩‍🎓Education & Qualification:

Ph.D. in Organic Chemistry:

  • Completed at Al-Azhar University, Cairo, Egypt.
  • Thesis Title: “Synthesis and Study of New Amino Acid Derivatives of Expected Biological Activities”.
  • Specialization: Amino Acids & Proteins.
  • Year of Completion: 2005-2008.

Master of Science (M.Sc.) in Organic Chemistry:

  • Earned at Al-Azhar University, Cairo, Egypt.
  • Thesis Title: “Synthesis and Study of Some Amino Acids Derivatives”.
  • Specialization: Amino Acids & Proteins.
  • Year of Completion: 2002-2005.

One-year Graduate Courses for M.Sc. Degree:

  • Partial fulfillment of the requirements for the M.Sc. degree.
  • Chemistry Department, Faculty of Science, Al-Azhar University, Cairo, Egypt.
  • Year: 2001.

Bachelor of Science (B.Sc.) in Special Chemistry:

  • Obtained from Al-Azhar University, Cairo, Egypt.
  • Year of Completion: 2000.

Professional Experience:  

Prof. Ahmed El-Henawy boasts a rich and extensive professional experience in the field of Chemistry, spanning over several roles and institutions. Since August 2008, he has served as a Lecturer in the Chemistry Department at Al-Azhar University, Cairo, Egypt, where he has been actively involved in teaching undergraduate and postgraduate courses, supervising theses, and contributing to curriculum development. Prior to this, from September 2005 to August 2008, he held the position of Assistant Lecturer at the same institution, where he further honed his teaching and academic skills. Prof. El-Henawy began his academic career as a Demonstrator at Al-Azhar University in September 2002, gaining valuable experience in laboratory instruction and student supervision. In addition to his roles at Al-Azhar University, he has also served as an Assistant Professor at Albaha University, Albaha, KSA, from October 2012 to the present, and as a Professor at Al-Azhar University, Cairo, Egypt, from February 2020 to the present. Throughout his career, Prof. El-Henawy has demonstrated a commitment to excellence in education, research, and academic leadership.

Research Interest:

Peptide Synthesis: Prof. El-Henawy explores the synthesis of novel dipeptide, tripeptide, tetrapeptide, and pentapeptide derivatives with potential antimicrobial activity. This research area involves designing and synthesizing peptide analogs to investigate their bioactivity against microbial pathogens.

Anticancer Agents: He is interested in the synthesis and evaluation of new analogs, such as 2-amino-1,3,4-thiadiazol derivatives, as potential anticancer agents. This research aims to develop novel compounds with enhanced anticancer activity and reduced toxicity profiles.

Small Molecule Drug Design: Prof. El-Henawy is involved in designing and synthesizing small molecule compounds with therapeutic potential. This includes the development of sulfonamide derivatives and other organic molecules with antimicrobial properties.

Biochemical Mechanisms: He investigates the biochemical mechanisms underlying the activity of synthesized compounds, focusing on their interaction with biological targets and elucidating their mode of action. This research contributes to understanding the molecular basis of drug efficacy and toxicity.

Spectroscopic Analysis: Prof. El-Henawy utilizes various spectroscopic techniques, such as UV spectroscopy, FTIR spectroscopy, and NMR spectroscopy, for structural elucidation and characterization of synthesized compounds. These analytical methods provide insights into the chemical structure and properties of organic molecules.

Publication Top Noted:

Title: Synthesis and characterization of some arylhydrazone ligand and its metal complexes and their potential application as flame retardant and antimicrobial additives

  • Authors: H Abd El-Wahab, M Abd El-Fattah, AH Ahmed, AA Elhenawy, NA Alian
  • Journal: Journal of Organometallic Chemistry
  • Volume: 791
  • Pages: 99-106
  • Year: 2015
  • Citations: 46

Title: Nano-amino acid cellulose derivatives: Eco-synthesis, characterization, and antimicrobial properties

  • Authors: M Hasanin, A El-Henawy, WH Eisa, H El-Saied, M Sameeh
  • Journal: International Journal of Biological Macromolecules
  • Volume: 132
  • Pages: 963-969
  • Year: 2019
  • Citations: 45

Title: Naproxen based 1, 3, 4-oxadiazole derivatives as EGFR inhibitors: Design, synthesis, anticancer, and computational studies

  • Authors: MM Alam, S Nazreen, ASA Almalki, AA Elhenawy, NI Alsenani, …
  • Journal: Pharmaceuticals
  • Volume: 14
  • Issue: 9
  • Pages: 870
  • Year: 2021
  • Citations: 41

Title: Experimental and theoretical investigation for 6-Morpholinosulfonylquinoxalin-2 (1H)-one and its haydrazone derivate: Synthesis, characterization, tautomerization and …

  • Authors: DM Elsisi, A Ragab, AA Elhenawy, AA Farag, AM Ali, YA Ammar
  • Journal: Journal of Molecular Structure
  • Volume: 1247
  • Pages: 131314
  • Year: 2022
  • Citations: 36

Title: Design, synthesis and molecular docking studies of thymol based 1, 2, 3-triazole hybrids as thymidylate synthase inhibitors and apoptosis inducers against breast cancer cells

  • Authors: MM Alam, AM Malebari, N Syed, T Neamatallah, ASA Almalki, …
  • Journal: Bioorganic & Medicinal Chemistry
  • Volume: 38
  • Pages: 116136
  • Year: 2021
  • Citations: 35

Eman Fayed | Pharmaceutical Organic Chemistry | Best Researcher Award

Posted on by Best Paper Award

Assoc Prof Dr. Eman Fayed, Pharmaceutical Organic Chemistry, Best Researcher Award

Associate Professor at Faculty of Pharmacy, Al-Azhar University, Egypt

Summary:

Dr. Eman Abdelmaboud Hamed Fayed is an Associate Professor of Pharmaceutical Organic Chemistry at the Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt. She obtained her Doctorate (Ph.D.) in Pharmaceutical Organic Chemistry from the same institution in November 2013, focusing on the synthesis and biological evaluation of new fused azepine derivatives. With over a decade of experience in academia, Dr. Fayed has held various teaching positions within the Pharmaceutical Organic Chemistry Department at Al-Azhar University, where she has been actively involved in teaching a wide range of courses at the undergraduate and postgraduate levels. In addition to her academic responsibilities, she has contributed significantly to the development of research and quality assurance initiatives within her faculty and has been recognized with several awards for her scientific research contributions. Dr. Eman Fayed’s research interests lie in pharmaceutical organic chemistry and drug discovery, with a focus on the synthesis, pharmacological evaluation, and design of novel organic compounds with potential therapeutic applications.

Professional Profile:

Scopus Profile

Google Scholar Profile

👩‍🎓Education & Qualification:

Doctorate (Ph.D.) in Pharmaceutical Organic Chemistry

  • Institution: Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt
  • Year of Completion: November 2013
  • Thesis Title: “Synthesis and Biological Evaluation of Some New Fused Azepine Derivatives”

Master’s degree (M.Sc) in Pharmaceutical Organic Chemistry

  • Institution: Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt
  • Year of Completion: July 2010
  • Thesis Title: “Synthesis and Pharmacological Evaluation of 5-Oxo-1, 4-Oxazepine Derivatives”

Bachelor’s degree (B.Sc) in Pharmaceutical Sciences

  • Institution: Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt
  • Year of Completion: May 2004
  • Academic Achievement: Excellent with honors

Professional Experience:  

Dr. Eman Abdelmaboud Hamed Fayed has gained extensive professional experience in academia, research, and pharmaceutical industries. Her career trajectory is as follows:

Associate Professor in Pharmaceutical Organic Chemistry Department

  • Institution: Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt
  • Duration: 2018 – Present

Lecturer in Pharmaceutical Organic Chemistry Department

  • Institution: Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt
  • Duration: 2013 – 2018

Assistant Lecturer in Pharmaceutical Organic Chemistry Department

  • Institution: Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt
  • Duration: 2010 – 2013

Demonstrator in Pharmaceutical Organic Chemistry Department

  • Institution: Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt
  • Duration: 2006 – 2010

Pharmacist in the Quality Control Unit

  • Organization: Holding Company for Vaccines (VACSERA)
  • Duration: 2005 – 2006

Dr. Eman Fayed’s roles have involved teaching various courses in pharmaceutical organic chemistry, supervising research activities, and contributing to the academic and administrative functions of the institutions she has been associated with. Additionally, her experience as a pharmacist in the quality control unit has provided her with practical insights into pharmaceutical industries.

Research Interest:

Dr. Eman Abdelmaboud Hamed Fayed’s research interests encompass various areas within pharmaceutical organic chemistry and related fields. Some of her key research interests include:

Synthesis of Novel Organic Compounds: Investigation and synthesis of new organic compounds with potential pharmacological applications.

Pharmacological Evaluation: Evaluation of the pharmacological properties and activities of synthesized organic compounds, including their efficacy, safety, and mechanism of action.

Drug Design and Development: Designing and developing new drugs or drug candidates with improved therapeutic profiles, including enhanced efficacy, reduced side effects, and improved bioavailability.

Heterocyclic Chemistry: Study of heterocyclic compounds and their synthesis, characterization, and pharmacological significance.

Spectroscopic Techniques: Application of various spectroscopic techniques for the structural elucidation and characterization of organic compounds.

Nutraceuticals and Natural Products: Investigation of natural products and nutraceuticals for their potential pharmacological activities and health benefits.

Organic Synthesis Methodologies: Development and optimization of organic synthesis methodologies for the efficient and sustainable synthesis of bioactive compounds.

Dr. Eman Fayed’s multidisciplinary research interests aim to contribute to the advancement of pharmaceutical sciences, drug discovery, and the development of novel therapeutic agents with clinical relevance and societal impact.

Publication Top Noted:

Title: Novel fluorinated pyrazole-based heterocycles scaffold: cytotoxicity, in silico studies and molecular modelling targeting double mutant EGFR L858R/T790M as antiproliferative and apoptotic agents

  • Journal: Medicinal Chemistry Research
  • Year: 2023
  • Volume: 32
  • Issue: 2
  • Pages: 369–388
  • Authors: E.A. Fayed, N.A. Gohar, A.H. Bayoumi, Y.A. Ammar

Title: Development of new spiro[1,3]dithiine-4,11′-indeno[1,2-b]quinoxaline derivatives as S. aureus Sortase A inhibitors and radiosterilization with molecular modeling simulation

  • Journal: Bioorganic Chemistry
  • Year: 2023
  • Volume: 131
  • Pages: 106307
  • Authors: A. Ragab, M.S. Abusaif, N.A. Gohar, E.A. Fayed, Y.A. Ammar

Title: Design, synthesis, and biological evaluation of a novel series of thiazole derivatives based on pyrazoline as anticancer agents

  • Journal: Egyptian Journal of Chemistry
  • Year: 2022
  • Volume: 65
  • Issue: 132
  • Pages: 1241–1252
  • Authors: U. Fathy, M.N.M. Yousif, E.M. Mohi El-Deen, E.A. Fayed

Title: Evaluation of quinoxaline derivatives as potential ergosterol biosynthesis inhibitors: design, synthesis, ADMET, molecular docking studies, and antifungal activities

  • Journal: Journal of Molecular Structure
  • Year: 2022
  • Volume: 1267
  • Pages: 133578
  • Authors: E.A. Fayed, M.A. Ebrahim, U. Fathy, H.S.E. Saeed, W.S. Khalaf

Title: The effect of novel synthetic semicarbazone- and thiosemicarbazone-linked 1,2,3-triazoles on the apoptotic markers, VEGFR-2, and cell cycle of myeloid leukemia

  • Journal: Bioorganic Chemistry
  • Year: 2022
  • Volume: 127
  • Pages: 105968
  • Authors: E.M. Othman, E.A. Fayed, E.M. Husseiny, H.S. Abulkhair