ย Dr. Hind Rafei | Medicine and Dentistry | Best Research Article Award
Dr at MD Anderson Cancer Center, United States.
Dr. Hind Rafei, MD, MS, ๐ฑ๐ง is an accomplished Assistant Professor at MD Anderson Cancer Center specializing in stem cell transplantation and cellular therapy. ๐ฌ Her pioneering research focuses on enhancing CAR-NK cell immunotherapy for solid tumors by targeting immunometabolic pathways and overcoming tumor microenvironment barriers. ๐ She has secured multiple high-impact grants, holds innovative patents, and is advancing several first-in-human trials. ๐ As Associate Director of Education and Fellowship, she mentors the next generation of physician-scientists while serving on prestigious review committees globally. ๐ With deep expertise bridging bench to bedside, Dr. Rafeiโs groundbreaking work promises safer, off-the-shelf cellular therapies for hard-to-treat cancers, making her a true leader and visionary in cancer immunotherapy. ๐งฌ
๐ Education
Dr. Hind Rafei ๐ฑ๐ง has a stellar academic background, graduating with a BS in Biology (High Distinction) and an MD (Alpha Omega Alpha) from the American University of Beirut ๐. She expanded her expertise with a Masterโs in Cancer Biology and Immunology from MD Anderson Cancer Centerโs Graduate School (GPA 4.0) ๐. Her education reflects a perfect blend of rigorous clinical training and cutting-edge laboratory research. Additional postgraduate fellowships at the NIH and MD Anderson in CAR-NK cell therapy enriched her scientific vision ๐ฌ. This elite training equipped Dr. Rafei with multidisciplinary knowledge spanning internal medicine, hematology-oncology, cancer immunotherapy, and cellular therapy design. Her education showcases her commitment to bridging lab research with real-world cancer care, positioning her as a role model for clinician-scientists globally ๐.
๐ผ Professional Experience
Dr. Rafeiโs professional experience is a testament to her dedication to translational cancer research and patient care ๐ฅ. She trained in Internal Medicine at The George Washington University, followed by Hematology and Medical Oncology at MD Anderson, where she also advanced CAR-NK cell research ๐ฌ. Currently an Assistant Professor in Stem Cell Transplant and Cellular Therapy and Associate Director of Education, she mentors fellows and leads research initiatives ๐ค. Her dual faculty roles in Immunology and Cancer Biology highlight her cross-disciplinary impact. From pioneering lab-based NK cell engineering to participating in early-phase clinical trials, Dr. Rafei demonstrates seamless integration of bench-to-bedside research. Her leadership on institutional committees and career expos further underscores her commitment to collaborative science and mentorship ๐.
๐ฌ Research Interest
Dr. Rafeiโs research passion centers on developing next-generation engineered CAR-NK cell therapies to combat treatment-resistant solid tumors ๐งฌ. She explores how modulating immunometabolism and targeting the tumor microenvironment can enhance cellular therapiesโ potency and persistence. Her projects span renal cell carcinoma, pancreatic, and ovarian cancers, pushing the frontiers of off-the-shelf NK cell immunotherapies ๐. With a focus on genetic engineering, epigenetic reprogramming, and metabolic fitness, Dr. Rafei bridges cutting-edge molecular biology with translational medicine. She actively pursues novel combination strategies, like pairing CAR-NK cells with HIF2a inhibition, to overcome immune resistance. Her research embodies innovation with a clear goal: safer, scalable, and more effective immunotherapies that reshape the landscape of solid tumor treatment ๐.
๐ Awards and Honors
Dr. Rafeiโs excellence is highlighted by numerous prestigious honors, including the ASCO Young Investigator Award, Clifton D. Howe Award, and multiple institutional merit grants ๐ . She is a two-time Alpha Omega Alpha Honor Medical Society inductee, demonstrating both academic distinction and leadership ๐๏ธ. Recognitions like the Joseph E. Johnson Leadership Award and institutional research fellowships underscore her dual strength as a clinician and researcher. Her selection for competitive training workshops and peer review programs reflects her growing influence in the cancer research community โจ. These accolades validate her innovative contributions to cellular immunotherapy and her dedication to advancing the field through mentorship and clinical trials. Each award strengthens her credibility as a promising leader in cancer immunology ๐.
๐งช Research Skills
Dr. Rafei brings an impressive portfolio of research skills spanning lab and clinical domains ๐ฌ. Her expertise includes genetic engineering, CRISPR-Cas9 editing, NK cell immunometabolism, xenograft modeling, and preclinical validation of novel cellular therapies ๐งฌ. She leads multi-institutional translational protocols, writes successful grant applications, and manages complex projects across large collaborative teams ๐. Her ability to design and translate laboratory findings into early-phase clinical trials sets her apart as a clinician-scientist. Skilled in immunology, tumor biology, and innovative protocol development, she stays at the forefront of adoptive cell therapy research. Her collaborations with top mentors and global research networks showcase her talent for bridging diverse expertise into actionable breakthroughs, ensuring her work remains impactful and clinically relevant ๐.
๐ Publication Details
Title: Role of baseline echocardiography prior to initiation of anthracycline-based chemotherapy in breast cancer patients
Authors: Mina A., Rafei H., Khalil M., Hassoun Y., Nasser Z., Tfayli A.
Year: 2015
Citation: BMC Cancer. 2015 Jan; 15(10). PMID: 25605569
Source: BMC Cancer
Title: Chemotherapy induced inflammation due to cosmetic oils: A case report
Authors: Hassoun Y., Khoury N.J., Rafei H., Mina A., Tfayli A.
Year: 2015
Citation: Case Reports in Internal Medicine. 2015 Jul; 2(3): 49-51
Source: Case Reports in Internal Medicine
Title: Pleurodesis in malignant pleural effusions: Outcome and predictors of success
Authors: Rafei H., Jabak S., Mina A., Tfayli A.
Year: 2015
Citation: Integrative Cancer Science and Therapeutics. 2015 Sep; 2(5): 216-221
Source: Integrative Cancer Science and Therapeutics
Title: Beer Potomania: A Challenging Case of Hyponatremia
Authors: Rafei H., Yunus R., Khurana P.
Year: 2016
Citation: Journal of Endocrinology and Metabolism. 2016 Sep; 6(4): 123-126
Source: Journal of Endocrinology and Metabolism
Title: Perspective of Lebanese oncologists on the symptom burden among adult cancer patients
Authors: Rafei H., Khalil M., Hassoun Y., Mina A., Nasser Z., Tfayli A.
Year: 2016
Citation: Lebanese Medical Journal. 2016 Dec; 64(4): 200-204. PMID: 29845844
Source: Lebanese Medical Journal
Title: Prevalence of EGFR and ALK Mutations in Lung Adenocarcinomas in the Levant Area – a Prospective Analysis
Authors: Tfayli A., Rafei H., Mina A., Khalil M., Fakhreddine N., Mahfouz R., et al.
Year: 2017
Citation: Asian Pacific Journal of Cancer Prevention. 2017 Jan; 18(1): 107-114. PMID: 28240017
Source: Asian Pacific Journal of Cancer Prevention
Title: Combination targeted pulmonary hypertension therapy in the resolution of dasatinib-associated pulmonary arterial hypertension
Authors: Jose A., Rafei H., Ahari J.
Year: 2017
Citation: Pulmonary Circulation. 2017 Jan; 7(4): 803-807. PMID: 28644066
Source: Pulmonary Circulation
Title: A rare breed: Wild-type BRAF and IgHV expression in a 29 year old lady with classical hairy cell leukemia
Authors: Hossain A., Rafei H., Jariwala A., El-Shami K.
Year: 2017
Citation: Leukemia Research Reports. 2017 Jan; 7: 20-22. PMID: 28275540
Source: Leukemia Research Reports
Title: Immune-based Therapies for Non-small Cell Lung Cancer
Authors: Rafei H., El-Bahesh E., Finianos A., Nassereddine S., Tabbara I.
Year: 2017
Citation: Anticancer Research. 2017 Feb; 37(2): 377-387. PMID: 28179283
Source: Anticancer Research
Title: Disseminated intravascular coagulation-like reaction following rituximab infusion
Authors: Rafei H., Nassereddine S., Garcia I.F.
Year: 2017
Citation: BMJ Case Reports. 2017 Feb; pii: bcr2016218443. PMID: 28179388
Source: BMJ Case Reports
โ Conclusion
In summary, Dr. Hind Rafei is a dynamic physician-scientist whose elite education ๐, robust professional experience ๐ผ, cutting-edge research ๐ฌ, decorated honors ๐, and advanced lab-to-clinic skills ๐งช uniquely position her as a trailblazer in cancer immunotherapy. Her pioneering work with engineered CAR-NK cells is shaping the future of solid tumor treatments, tackling critical barriers like immunosuppression and tumor heterogeneity ๐. Through impactful leadership, mentorship, and groundbreaking clinical trials, Dr. Rafei is transforming innovation into hope for patients worldwide ๐. Her unwavering dedication, collaborative spirit, and relentless pursuit of safer, scalable therapies make her a deserving candidate for any top-tier recognition celebrating research excellence and translational impact โญ.