Douâae Ou-Yahia | Immunology and Microbiology | Editorial Board Member

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Dr. Douâae Ou-Yahia | Immunology and Microbiology | Editorial Board Member 

Chercheur associé | Sidi Mohamed Ben Abdellah University | Morocco

Douâae Ou-Yahia is a researcher whose work primarily focuses on the bioactive properties and pharmacological potential of plant-derived compounds, particularly essential oils and polyphenols from Moroccan flora. Her research encompasses the evaluation of antioxidant, antimicrobial, cytotoxic, and genotoxic effects of various plant extracts, with a strong emphasis on discovering novel therapeutic agents, especially against breast cancer. In 2023, she co-authored several notable studies, including investigations into Ptychotis verticillata essential oil, demonstrating its antioxidant activity and potential as a breast cancer therapeutic, and studies on Mentha piperita, exploring how irrigation water quality affects its chemical profile and secondary metabolites, with implications for pharmacological applications. She has also extensively studied carob (Ceratonia siliqua var. Rahma) leaves, analyzing their polyphenol content, antimicrobial activity, cytotoxicity against cancer cell lines, and genotoxicity, highlighting their multi-faceted potential as functional bioactive compounds. Her research combines both in vitro and in silico approaches, integrating analytical profiling, chemical characterization, and computational modeling to better understand plant bioactivity and optimize therapeutic applications. Beyond her laboratory work, Douâae Ou-Yahia contributes to advancing the scientific understanding of medicinal plants in Morocco, providing insights that may support the development of natural and effective treatments. Her publications, appearing in journals such as Life, International Journal of Plant Biology, Pharmaceuticals, and Antibiotics, reflect a commitment to rigorous experimental design and multidisciplinary collaboration with other experts in the fields of pharmacology, chemistry, and plant biology. Overall, her work bridges fundamental phytochemical research and applied biomedical science, offering promising avenues for natural product-based therapies and contributing to global efforts in exploring sustainable, plant-based solutions for healthcare challenges.

Profile: ORCID

Featured Publications

  1. Taibi, M., Elbouzidi, A., Ouahhoud, S., Loukili, E. H., Ou-Yahia, D., Ouahabi, S., Alqahtani, A. S., Noman, O. M., Addi, M., Bellaouchi, R., et al. (2023). Evaluation of antioxidant activity, cytotoxicity, and genotoxicity of Ptychotis verticillata essential oil: Towards novel breast cancer therapeutics. Life, 13(7), 1586.

  2. Haddou, M., Taibi, M., Elbouzidi, A., Loukili, E. H., Yahyaoui, M. I., Ou-Yahia, D., Mehane, L., Addi, M., Asehraou, A., Chaabane, K., et al. (2023). Investigating the impact of irrigation water quality on secondary metabolites and chemical profile of Mentha piperita essential oil: Analytical profiling, characterization, and potential pharmacological applications. International Journal of Plant Biology, 14(3), 49.

  3. Elbouzidi, A., Taibi, M., Ouassou, H., Ouahhoud, S., Ou-Yahia, D., Loukili, E. H., Aherkou, M., Mansouri, F., Bencheikh, N., Laaraj, S., et al. (2023). Exploring the multi-faceted potential of carob (Ceratonia siliqua var. Rahma) leaves from Morocco: A comprehensive analysis of polyphenols profile, antimicrobial activity, cytotoxicity against breast cancer cell lines, and genotoxicity. Pharmaceuticals, 16(6), 840.

  4. Taibi, M., Elbouzidi, A., Ou-Yahia, D., Dalli, M., Bellaouchi, R., Tikent, A., Roubi, M., Gseyra, N., Asehraou, A., Hano, C., et al. (2023). Assessment of the antioxidant and antimicrobial potential of Ptychotis verticillata Duby essential oil from Eastern Morocco: An in vitro and in silico analysis. Antibiotics, 12(4), 655.

  5. Elbouzidi, A., Taibi, M., Ou-Yahia, D., Loukili, E. H., & others. (2023). Exploring the multi-faceted potential of carob leaves from Morocco: A comprehensive analysis of polyphenols profile, antimicrobial activity, cytotoxicity against breast cancer cell lines, and genotoxicity. Preprint.

Douâae Ou-Yahia’s research advances the understanding of bioactive compounds from Moroccan plants, providing novel insights into natural antioxidants, antimicrobials, and cancer therapeutics. Her work bridges fundamental phytochemistry and applied biomedical science, contributing to healthcare innovation and sustainable, plant-based solutions with global impact.