Niraj Kumar | Structural Biology | Best Paper Award

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Mr. Niraj Kumar | Structural Biology | Best Paper Award

Niraj Kumar at UNESCO, Regional Centre For Biotechnology, India

Summary:

Mr. Niraj Kumar is a Ph.D. research scholar specializing in structural biology and translation regulation at the Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad. His research focuses on the survival mechanisms of Mycobacterium tuberculosis, particularly how the bacterium modifies protein synthesis under stress conditions. With expertise in cryo-EM and molecular biology techniques, Niraj has received international recognition for his work, winning the Best Cryo-EM Microstructure Award in 2024. His long-term goal is to deepen his understanding of ribosomal function using advanced cryo-EM techniques.

Professional Profile:

šŸ‘©ā€šŸŽ“Education:

Niraj Kumar completed his B.Sc. in Industrial Microbiology, Botany, and Chemistry from Ch. Charan Singh University, Meerut, in 2014. He then earned his M.Sc. in Microbiology from the same institution in 2016. Currently, he is pursuing his Ph.D. at the Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, Haryana, under the supervision of Dr. Prem S. Kaushal. His doctoral research, which began in 2019, focuses on structural biology and translation regulation in the context of Mycobacterium tuberculosis.

šŸ¢ Professional Experience:

As a Ph.D. research scholar, Niraj Kumar has gained significant experience in structural biology, with a particular emphasis on cryo-electron microscopy (cryo-EM). He is part of a cutting-edge research team that investigates how Mycobacterium tuberculosis adapts its translational mechanisms to survive in stressful environments, such as hypoxia. Nirajā€™s technical expertise includes cryo-EM sample preparation, ribosome purification, protein purification, gene cloning, site-directed mutagenesis, and X-ray crystallography. He has also mastered computational tools like Relion3.1.4, Coot, ChimeraX, PyMol, GROMACS, and more for single-particle reconstruction analysis.

In addition to his research, Nirajā€™s work has been recognized at the international level. He won the Best Cryo-EM Microstructure Award at the 2024 International Conference on Electron Microscopy organized by the Electron Microscope Society of India (EMSI). He has also qualified for several prestigious examinations, including the CSIR NET/JRF, ICAR NET-ARS, GATE in Life Sciences, and the ICAR NET in multiple years.

Research Interests:

Niraj Kumarā€™s research primarily focuses on how Mycobacterium tuberculosis adapts its protein synthesis machinery to survive under low-oxygen (hypoxic) conditions. Using cryo-EM single-particle reconstruction, he has studied the structure of the 70S ribosome in complex with the hibernation promotion factor (RafH), which is induced during hypoxia. His 2.8 ƅ resolution structure reveals that RafH binding blocks all three modes of translation initiation, shields the ribosome from degradation, and prevents ribosome-targeting antibiotics from binding. Moving forward, Niraj aims to expand his expertise in Cryo-electron tomography and Cryo-FIB SEM to further explore ribosome function in a cellular context under stress conditions.

Author Metrics:

Niraj Kumar is an emerging researcher with a growing body of work. His publication on the 70S ribosome structure with the RafH complex has garnered attention, contributing to the understanding of bacterial protein synthesis and antibiotic resistance. He continues to publish and present his research at scientific conferences, expanding his footprint in the field of structural biology.

Top Noted Publication:

The spectrum of neurologic disease associated with anti-GM1 antibodies

  • Authors: SA Sadiq, FP Thomas, K Kilidireas, S Protopsaltis, AP Hays, KW Lee, D Hays
  • Journal: Neurology
  • Volume: 40, Issue: 7, Page: 1067-1067
  • Year: 1990
  • Citations: 303

Paradigms of climate change impacts on some major food sources of the world: A review on current knowledge and future prospects

  • Authors: A Tripathi, DK Tripathi, DK Chauhan, N Kumar, GS Singh
  • Journal: Agriculture, Ecosystems & Environment
  • Volume: 216, Pages: 356-373
  • Year: 2016
  • Citations: 302

Federated learning enables big data for rare cancer boundary detection

  • Authors: S Pati, U Baid, B Edwards, M Sheller, SH Wang, GA Reina, P Foley, …
  • Journal: Nature Communications
  • Volume: 13, Article Number: 7346
  • Year: 2022
  • Citations: 178

Evaluation of OphthacareĀ® eye dropsā€”a herbal formulation in the management of various ophthalmic disorders

  • Authors: NR Biswas, SK Gupta, GK Das, N Kumar, PK Mongre, D Haldar, S Beri
  • Journal: Phytotherapy Research
  • Volume: 15, Issue: 7, Pages: 618-620
  • Year: 2001
  • Citations: 152

Development and evaluation of deep learningā€“based segmentation of histologic structures in the kidney cortex with multiple histologic stains

  • Authors: CP Jayapandian, Y Chen, AR Janowczyk, MB Palmer, CA Cassol, …
  • Journal: Kidney International
  • Volume: 99, Issue: 1, Pages: 86-101
  • Year: 2021
  • Citations: 133

Farhad Ghodsi | Thin Films

Posted on by Best Paper Award
Prof. Farhad Ghodsi: Leading Researcher in Thin Films

šŸŽ‰ Congratulations Prof. Farhad GhodsiĀ on Winning the Best Researcher Award! šŸ† Your dedication to research, mentorship, and collaboration with international teams is truly commendable. This award is a testament to your outstanding work and the impact it has on the broader community.

Short Bio:
Prof. Farhad Ghodsi is a Full Professor in the Department of Physics at the University of Guilan. With extensive experience, he has contributed significantly to the field of Physics, particularly in the fabrication and characterization of novel materials. Prof. Ghodsi has supervised numerous Master’s and Ph.D. students, showcasing his commitment to academic mentorship. His research, evidenced by over 650 reviews and impactful publications, reflects his dedication to advancing scientific knowledge.

Professional Profile:

šŸ“š Education:

  • Ph.D., Physics Engineering, Istanbul Technical University (ITU), 1999.
  • M.Sc., Physics Engineering, Istanbul Technical University (ITU), 1995.
  • B.Sc. (Hons), Physics Engineering, Istanbul Technical University (ITU), 1992.

šŸ¢ Current Positions:

  • Full Professor, Department of Physics, University of Guilan, 2011-present.

šŸ” Previous Positions:

  • Associate Professor, Department of Physics, University of Guilan, 2007-2011.
  • Assistant Professor, Department of Physics, University of Guilan, 1999-2007.

šŸ“ˆ Impact Factor:

  • Google Scholar Citations: 1978
    • h-index: 25
    • i10-index: 48
  • Scopus Citations: 1611
    • h-index: 22

šŸ” Reviews:

  • More than 650 reviews from 70 ISI indexed Journals published by Elsevier, Springer, IOP Science, John Wiley, Taylor & Francis, RSC, World Scientific, Kluwer, SciELO

šŸŽ“ Supervisor:

  • Master: 56 Students
  • PhD.: 16 Students

Publication Top Noted:

  • Fabrication of V2O5/NiO double-layer film with hydrophilic property and evaluation of the effects of V2O5 coating on electro-optical parameters of NiO film
  • Electrochemical and optical properties of magnetic CuFe2O4 nanofibers grown by PVP and PVA-assisted solā€“gel electrospinning
  • Crystalline phase change and improvement electro-optical parameters of SnSx thin films by different ambient
  • Electrospun MgCo2O4 nanofibers as an efficient electrode material for pseudocapacitor applications: Effect of calcination temperature on electrochemical performance
  • Effects of nitrogen incorporation on N-doped DLC thin film electrodes fabricated by dielectric barrier discharge plasma: Structural evolution and electrochemical performances
  • Investigating the effect of Zn doping on physical properties of nanostructured Sb2S3 thin films by dipā€‘coating technique
  • 4-Nitro-azo dye-sensitized optical behavior of organic/inorganic hybrid networks in zirconium-based thin films: effect of cu co-doping

Research Focus:

Prof. Farhad Ghodsi’s research focus encompasses various aspects of physics and materials science. His notable contributions include the fabrication and characterization of novel materials, with a keen interest in their electro-optical properties. Some key areas of his research focus include:

  1. Thin Film Technology
  2. Nanomaterials and Nanofibers
  3. Electrochemical Studies
  4. Doping Effects
  5. Supervision and Mentorship