P. V. G. K Sarma | Biochemistry | Editorial Board Member

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Assoc. Prof. Dr. P. V. G. K Sarma | Biochemistry | Editorial Board Member 

Associate Professor | Sri Venkateswara Institute of Medical Sciences | India

P. V. G. K. Sarma is a senior Indian biotechnologist and academic leader currently serving as the Head of the Department of Biotechnology at the Sri Venkateswara Institute of Medical Sciences, Tirupati, a position he has held since 2004, with his academic training from JNTU Hyderabad and a broad research portfolio reflected in over a hundred scholarly publications indexed across major journals. P. V. G. K. Sarma His core research spans genetic engineering, microbial biotechnology, functional genomics, structural bioinformatics, and stem cell differentiation with a strong translational focus on regenerative medicine and human disease. A major strength of his work lies in the in vitro differentiation of human CD34+ hematopoietic stem cells into diverse lineages including pancreatic β-cells, erythrocytes, podocytes, type-II pneumocytes, keratinocytes, chondrocytes, and megakaryocytes, contributing to the understanding of cellular plasticity and therapeutic cell generation. Parallel to this, he has made significant contributions to microbial pathogenesis, particularly on Staphylococcus aureus, elucidating molecular mechanisms of biofilm formation, metabolic regulation, and antimicrobial resistance, including MRSA, through gene expression, enzyme activity, and structure-based drug design approaches. His interdisciplinary research also addresses clinical and molecular genetics, with notable studies on mutations linked to congenital erythrocytosis, breast cancer, leukemia drug resistance, rheumatoid arthritis, tuberculosis susceptibility, cardiovascular disease, and pain genetics. During the COVID-19 period, his in silico investigations on antiviral compounds targeting SARS-CoV-2 proteins further demonstrated his adaptability across emerging biomedical challenges. He has consistently integrated wet-lab experimentation with computational biology, signaling pathways, and nanobiotechnology, including cytotoxicity studies of silver nanoparticles on human stem cells. Beyond research, he is actively involved in peer review for reputed international journals and contributes to clinical translational science through collaborations across medicine, genetics, and biotechnology. Collectively, his career reflects sustained leadership in Indian biomedical research, with impactful contributions to stem cell biology, microbial biotechnology, and molecular genetics aimed at advancing diagnostics, therapeutics, and regenerative strategies.

Profile: ORCID

Featured Publications

  1. Chandrasekhar, C., Kumar, P. S., & Sarma, P. V. G. K. (2019). Novel mutations in the kinase domain of BCR-ABL gene causing imatinib resistance in chronic myeloid leukemia patients. Scientific Reports, 9, 38672.

  2. Loganathan, S. E., Kattaru, S., Kodavala, S., Chandrasekhar, C., & Sarma, P. V. G. K. (2024). Prominent expression of COL2A1, ACAN and IHH genes observed in the differentiation of human hematopoietic stem cells into articular type of chondrocytes. Stem Cell Reviews and Reports, 20.

  3. Kodavala, S., Loganathan, S. E., Kattaru, S., Chandrasekhar, C., & Sarma, P. V. G. K. (2024). In vitro generation of epidermal keratinocytes from human CD34-positive hematopoietic stem cells. In Vitro Cellular & Developmental Biology – Animal, 60.

  4. Suthi, S., Mounika, A., & Sarma, P. V. G. K. (2023). Elevated acetate kinase (ackA) gene expression, activity, and biofilm formation observed in methicillin-resistant strains of Staphylococcus aureus. Journal of Genetic Engineering and Biotechnology, 21.

  5. Kattaru, S., Manne Mudhu, S., Loganathan, S. E., Kodavala, S., & Sarma, P. V. G. K. (2021). Increased insulin and GLUT2 gene expression and elevated glucokinase activity in β-like cells of islets of Langerhans differentiated from human haematopoietic stem cells on treatment with Costus igneus leaf extract. Molecular Biology Reports, 48.

P. V. G. K. Sarma has advanced translational biotechnology through pioneering stem cell differentiation, molecular genetics, and microbial pathogenesis research that directly supports regenerative medicine and precision diagnostics. His work bridges laboratory science with clinical and industrial applications, contributing to improved disease understanding, therapeutic development, and global biomedical innovation.

Ms. Shahrzad Manavi Nameghi | Biochemistry | Best Researcher Award

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Ms. Shahrzad Manavi Nameghi | Biochemistry | Best Researcher Award

Researcher | Islamic Azad University Tehran Medical Sciences | Iran

Shahrzad Manavi Nameghi is an accomplished molecular genetics researcher from Tehran, Iran, recognized for her work in diabetes, cancer pathways, gene therapy, and stem cell research. She completed her M.Sc. in Molecular Biology-Genetics at Islamic Azad University, Tehran Medical Sciences in 2019, where her thesis focused on the relation between the GIPR gene and type 2 diabetes, following a B.Sc. in Cellular and Molecular Biology-Genetics from Shahid Bahonar University, Kerman in 2017. Professionally, she has served as a lab technician and R&D assistant at Khazar Lab, Tehran, and as a main lab technician at Mendel Medical Genetics Laboratory, contributing to projects involving DNA and RNA extraction, real-time PCR, pyro-sequencing, ARMS-PCR, MLPA-PCR, and other molecular techniques. She has also worked as a research assistant at the Endocrine and Metabolism Research Institute, gaining expertise in RFLP-PCR and sequencing analysis. Her research interests include molecular genetics, diabetes and cancer-related gene pathways, gene therapy, and stem cell therapy, and she is proficient in analytical techniques such as ELISA, fragment analysis, primer design, and basic R programming. Shahrzad has published multiple peer-reviewed articles in indexed journals including Gene Reports, Endocrine and Metabolic Science, and Regenerative Biology and Medicine, with a growing citation count of 15 and h-index of 2, and serves as an editor and peer reviewer for biomedical journals. She has presented her work at international conferences, including the IDF Congress in Korea and Brussels, and completed various certifications and workshops in peer review, manuscript preparation, laboratory techniques, and molecular biology. Her achievements, dedication to research, and involvement in scientific communities underscore her leadership potential and commitment to advancing biomedical science. For her significant contributions to molecular genetics, diabetes, and cancer research, and her active role in knowledge dissemination and mentorship, Shahrzad Manavi Nameghi is a highly deserving candidate for the Best Researcher Award.

Profiles: Google Scholar | ORCID | Scopus | LinkedIn | ResearchGate

Featured Publications

  1. Manavi Nameghi, S. (2024). Unraveling the molecular genetic basis of type 2 diabetes. Journal of Gene Reports. CiteScore: 3.3. Citations: 4. H-index: 2.

  2. Manavi Nameghi, S. (2024). Exploring the recent advancement and future prospects of personalized medicine in type 2 diabetes. Journal of Endocrine and Metabolic Science. CiteScore: 2.8.

  3. Manavi Nameghi, S. (2023). Cancer stem cells as a considerable barrier in anti-cancer treatments. Journal of Regenerative Biology and Medicine. CiteScore: 7.

  4. Manavi Nameghi, S. (2023). Association of GIPR gene variant on the risk of type 2 diabetes: A case control study. Journal of Endocrine and Metabolic Science. CiteScore: 2.8.

  5. Manavi Nameghi, S. (2022). Investigating the highlights of pluripotent stem cells in type 2 diabetes. Journal of Regenerative Biology and Medicine. CiteScore: 7.