P. V. G. K Sarma | Biochemistry | Editorial Board Member

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Assoc. Prof. Dr. P. V. G. K Sarma | Biochemistry | Editorial Board Member 

Associate Professor | Sri Venkateswara Institute of Medical Sciences | India

P. V. G. K. Sarma is a senior Indian biotechnologist and academic leader currently serving as the Head of the Department of Biotechnology at the Sri Venkateswara Institute of Medical Sciences, Tirupati, a position he has held since 2004, with his academic training from JNTU Hyderabad and a broad research portfolio reflected in over a hundred scholarly publications indexed across major journals. P. V. G. K. Sarma His core research spans genetic engineering, microbial biotechnology, functional genomics, structural bioinformatics, and stem cell differentiation with a strong translational focus on regenerative medicine and human disease. A major strength of his work lies in the in vitro differentiation of human CD34+ hematopoietic stem cells into diverse lineages including pancreatic β-cells, erythrocytes, podocytes, type-II pneumocytes, keratinocytes, chondrocytes, and megakaryocytes, contributing to the understanding of cellular plasticity and therapeutic cell generation. Parallel to this, he has made significant contributions to microbial pathogenesis, particularly on Staphylococcus aureus, elucidating molecular mechanisms of biofilm formation, metabolic regulation, and antimicrobial resistance, including MRSA, through gene expression, enzyme activity, and structure-based drug design approaches. His interdisciplinary research also addresses clinical and molecular genetics, with notable studies on mutations linked to congenital erythrocytosis, breast cancer, leukemia drug resistance, rheumatoid arthritis, tuberculosis susceptibility, cardiovascular disease, and pain genetics. During the COVID-19 period, his in silico investigations on antiviral compounds targeting SARS-CoV-2 proteins further demonstrated his adaptability across emerging biomedical challenges. He has consistently integrated wet-lab experimentation with computational biology, signaling pathways, and nanobiotechnology, including cytotoxicity studies of silver nanoparticles on human stem cells. Beyond research, he is actively involved in peer review for reputed international journals and contributes to clinical translational science through collaborations across medicine, genetics, and biotechnology. Collectively, his career reflects sustained leadership in Indian biomedical research, with impactful contributions to stem cell biology, microbial biotechnology, and molecular genetics aimed at advancing diagnostics, therapeutics, and regenerative strategies.

Profile: ORCID

Featured Publications

  1. Chandrasekhar, C., Kumar, P. S., & Sarma, P. V. G. K. (2019). Novel mutations in the kinase domain of BCR-ABL gene causing imatinib resistance in chronic myeloid leukemia patients. Scientific Reports, 9, 38672.

  2. Loganathan, S. E., Kattaru, S., Kodavala, S., Chandrasekhar, C., & Sarma, P. V. G. K. (2024). Prominent expression of COL2A1, ACAN and IHH genes observed in the differentiation of human hematopoietic stem cells into articular type of chondrocytes. Stem Cell Reviews and Reports, 20.

  3. Kodavala, S., Loganathan, S. E., Kattaru, S., Chandrasekhar, C., & Sarma, P. V. G. K. (2024). In vitro generation of epidermal keratinocytes from human CD34-positive hematopoietic stem cells. In Vitro Cellular & Developmental Biology – Animal, 60.

  4. Suthi, S., Mounika, A., & Sarma, P. V. G. K. (2023). Elevated acetate kinase (ackA) gene expression, activity, and biofilm formation observed in methicillin-resistant strains of Staphylococcus aureus. Journal of Genetic Engineering and Biotechnology, 21.

  5. Kattaru, S., Manne Mudhu, S., Loganathan, S. E., Kodavala, S., & Sarma, P. V. G. K. (2021). Increased insulin and GLUT2 gene expression and elevated glucokinase activity in β-like cells of islets of Langerhans differentiated from human haematopoietic stem cells on treatment with Costus igneus leaf extract. Molecular Biology Reports, 48.

P. V. G. K. Sarma has advanced translational biotechnology through pioneering stem cell differentiation, molecular genetics, and microbial pathogenesis research that directly supports regenerative medicine and precision diagnostics. His work bridges laboratory science with clinical and industrial applications, contributing to improved disease understanding, therapeutic development, and global biomedical innovation.

Dr. Mostafa Saberian | Biochemistry | Best Researcher Award

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Dr. Mostafa Saberian | Biochemistry | Best Researcher Award

Lecturer | Tehran University of Medical Sciences | Iran

Prof. Mostafa Saberian is highly suitable for the Best Researcher Award, reflecting a distinguished career in medical laboratory sciences at Tehran University of Medical Sciences since 2009, with prior professional activity dating back to 2008. His research contributions encompass a diverse range of impactful studies, including molecular and clinical investigations on calcium channels in anesthesia, innovative hydrogel-based approaches for tissue engineering and wound healing, and regenerative medicine applications using mesenchymal stem cells. Notably, his work has been published in high-quality journals such as Molecular Pain, Tissue Engineering Part B: Reviews, Heliyon, and the Journal of Professional Nursing, demonstrating both breadth and depth in biomedical research. He has also made significant contributions to clinical studies, including investigations on fluid balance in post-operative acute kidney injury and the impact of probiotics and natural compounds on cellular proliferation, highlighting a translational focus bridging laboratory research and clinical applications. Beyond his publications, Prof. Saberian has actively engaged in peer review, contributing 33 reviews across seven prestigious journals, which underscores his commitment to advancing scientific rigor and supporting the broader research community. His interdisciplinary approach, combining molecular biology, tissue engineering, regenerative medicine, and clinical insights, reflects innovative thinking and a capacity to address complex biomedical challenges. Additionally, his collaboration with both national and international researchers emphasizes his ability to foster partnerships and contribute to global scientific discourse. Overall, Prof. Saberian’s sustained scholarly productivity, impactful research outputs, and dedication to mentoring and peer review make him a highly deserving candidate for the Best Researcher Award, recognizing not only his academic excellence but also his leadership and influential presence in advancing medical and biomedical sciences at both national and international levels.

Profiles: Google Scholar | Scopus | ORCID | ResearchGate

Featured Publications

  1. Saberian, M., Shamsi, A., Mohseni, M. M., Taghizadehimani, A., & Shahidi Delshad, E. (2025). Calcium channels in anesthesia management: A molecular and clinical review. Molecular Pain.

  2. Molaei, R., Hosseinkhani, A., & Saberian, M. (2025). Molecular regulation of tissue remodeling through chitosan-based hydrogels in wound healing dynamics. Tissue Engineering Part B: Reviews.

  3. Saberian, M., Safari Roudsari, R., Haghshenas, N., Rousta, A., & Alizadeh, S. (2024). How the combination of alginate and chitosan can fabricate a hydrogel with favorable properties for wound healing. Heliyon.

  4. Saberian, M., Abak, N. (2024). Hydrogel-mediated delivery of platelet-derived exosomes: Innovations in tissue engineering. Heliyon.

  5. Shahidi Delshad, E., Nobahar, M., Raiesdana, N., Yarahmadi, S., & Saberian, M. (2023). Academic resilience, moral perfectionism, and self-compassion among undergraduate nursing students: A cross-sectional, multi-center study. Journal of Professional Nursing.