Prof. Hayder Giha: Leading Researcher in Medical biochemistry

🎉 Congratulations Prof. Hayder Giha on Winning the Best Paper Award! 🏆 Your dedication to research, mentorship, and collaboration with international teams is truly commendable. This award is a testament to your outstanding work and the impact it has on the broader community.

Professional Profile:

• Scopus Profile 
• Orcid Profile
• Research Gate

🩺🧬 Summary: He is a Medical Doctor (MD), Ph.D., and Professor of Medical Biochemistry and Molecular Biology. Currently teaching Medical Biochemistry, Cell and Molecular Biology, and Genetics to undergraduate medical students and postgraduates. In my research career, He published approximately 77 articles in peer-reviewed international journals with good impact factors (IF between 0.00 to 47).

He is research journey began with a focus on malaria, particularly simple and severe P. falciparum malaria. He delved into clinical epidemiology, antigenic variation, and natural immunity against vaccine candidate antigens. He later shifted my focus to metabolic disorders, specifically type 2 diabetes mellitus (T2D) and obesity, exploring the roles of vitamin D and gut hormones. My current research plan emphasizes biomarkers as diagnostic tools and pathophysiological markers, with a keen interest in inborn errors of metabolism and T2D. T2D studies include diabetes pathophysiology, insulin resistance, and mitochondrial dysfunction, considering factors like oxidative stress, chronic inflammation, and chronic metabolic acidosis.

🎓 Education and Qualifications:

• MBBS (Bachelor of Medicine), University of Khartoum, Sudan, Oct 1988.
• Ph.D., University of Copenhagen, Denmark, Jul 1999. Thesis title: “Antigenic variation in Plasmodium falciparum malaria: studies from an area of seasonal and unstable transmission.”
• Other overseas training: Molecular Biology Applications, Edinburgh University, UK, June-July 1996.
• Post-doctoral training: Application of molecular techniques in prediction of drug resistance in malaria infections, International Atomic Energy Agency (IAEA), Edinburgh University, 2002 (3 months).

📚 Publications Top Noted:

1. Giha HA. Hidden chronic metabolic acidosis of diabetes type 2 (CMAD): Clues, causes and consequences. Rev Endocr Metab Disord. 2023 Aug;24(4):735-750.
2. Alamin OASO, Elgalil FMA, Giha HA. Warfarin prophylaxis for arterial thromboembolism: Age is the prime dose determinant and atrial fibrillation is the main indication in an Afro-Arab Ethinic community. Open J Clin Med Case Rep. 2023.
3. Giha HA, Abdulwahab RA, Abbas J, Shinwari Z, Alaiya A. Sex-Biased Expression of Genes Allocated in the Autosomal Chromosomes: Blood LC-MS/MS Protein Profiling in Healthy Subjects. Genet Res (Camb). 2023 Mar 11;2023:8822205.
4. Sater MS, AlDehaini DMB, Malalla ZHA, Ali ME, Giha HA. Plasma IL-6, TREM1, uPAR, and IL6/IL8 biomarkers increment further witnessing the chronic inflammation in type 2 diabetes. Horm Mol Biol Clin Investig. 2023 Feb 28.
5. Alamin OAO, Amir O, Giha HA. Correlates and Severity of Left Ventricular Hypertrophy in Type 2 Diabetes Patients in an Afro-Arab-cross Ethnic Community. Cardiology Research and Reports. 2022, 4(4); DOI: 10.31579/2692-9759/054.

🔬 Research Projects:

• Malaria
• Metabolic Syndrome and Obesity
• Vitamin D and Vitamin D Receptor Polymorphism
• Inborn Errors of Metabolism
• Virtual Biochemistry Lab Project
• Traffic Road Accidents

Research Focus:

Hayder Giha’s research focus spans several areas in the fields of medical biochemistry, molecular biology, and genetics. Below are the key areas of research that he has been involved in:

1. Malaria Research:
   • Initially, he conducted research in the field of malaria, specifically focusing on simple and severe P. falciparum malaria.
   • Areas of interest included clinical epidemiology, antigenic variation, and natural immunity against vaccine candidate antigens.
   • Molecular characterization of malaria parasites, drug resistance, and the relationship between parasite virulence and resistance.
2. Metabolic Disorders Research:
   • Transitioned to studying metabolic disorders, particularly type 2 diabetes mellitus (T2D) and obesity.
   • Investigated the role of vitamin D and gut hormones in metabolic disorders.
3. Biomarkers and Pathophysiological Markers:
   • His current research plan emphasizes the use of biomarkers as diagnostic tools and novel pathophysiological markers for diseases.
   • Special interest in inborn errors of metabolism and T2D.
   • Focus on diabetes pathophysiology, insulin resistance, mitochondrial dysfunction, oxidative stress, chronic inflammation, and chronic metabolic acidosis.
4. Publication Highlights:
   • Published approximately 77 articles in peer-reviewed international journals with varying impact factors.
   • Papers cover a range of topics from malaria to metabolic disorders.
5. Research Projects:
   • Involved in various research projects related to malaria, metabolic syndrome, obesity, vitamin D, vitamin D receptor polymorphism, inborn errors of metabolism, and a Virtual Biochemistry Lab Project.
   • Contributed to the study of traffic road accidents.

Overall, Dr. Hayder Giha has made significant contributions to understanding diseases at the molecular level, with a focus on infectious diseases like malaria and metabolic disorders such as diabetes. His work includes both basic research and contributions to clinical understanding, emphasizing the development of diagnostic tools and markers for diseases.